The research team at the Center for Chemical Biology and Biotechnology (C2B2) and Center for Drug Discovery and Development (CND3) led by Dr. Doralyn S. Dalisay and Dr. Jonel P. Saludes has discovered antibiotics from a bacteria thriving in marine sediments of the Philippines.
The antibiotics kill the multidrug-resistant Staphylococcus aureus (MDRSA), a pathogen that causes a range of illnesses from minor skin infections to life-threatening diseases, by breaking the protective membrane of the cell. The findings of this research provide evidence that these antibiotics potentially serve as leads to combat antibiotic-resistant pathogens.
The research paper was reviewed by antibiotic experts from Italy and Russia and was published in high impact international journal, Frontiers in Microbiology today, April 24, 2020.
Frontiers in Microbiology, one of the most cited microbiology Q1 journals, has an Impact Factor of 4.259 and publishes rigorously peer-reviewed manuscripts across the entire spectrum of microbiology.
This research is made possible through a grant awarded to University of San Agustin by the Grant-in-Aid Program of the National Research Council of the Philippines (NRCP) and Department of Science and Technology (DOST).
Read more about the discoveries in Frontiers in Microbiology website: https://doi.org/10.3389/fmicb.2020.00743.
The research paper is co-authored by Melissa June Paderog (Faculty, Department of Pharmacy and C2B2), Angelica Faith Suarez (Research Associate, C2B2), Edna Sabido (Research Associate, CND3), and Dr. Zhen Jie Low (Waters Pacific Pte Ltd, Singapore). (via University of San Agustin – Iloilo Facebook)